Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness?
نویسندگان
چکیده
منابع مشابه
Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness?
Whether mouse models of chronic asthma can be used to investigate the relationship between airway inflammation/remodeling and airway hyper-responsiveness (AHR) is a vexed question. It raises issues about the extent to which such models replicate key features of the human disease. Here, we review some of the characteristic pathological features of human asthma and their relationship to AHR and e...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2012
ISSN: 1664-042X
DOI: 10.3389/fphys.2012.00312